Search on: 2-OXO ACID CARBOXY-LYASE 
Descriptors Found: 1
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 1 / 1 DeCS     
Descriptor English:   Pyruvate Decarboxylase 
Descriptor Spanish:   Piruvato Descarboxilasa 
Descriptor Portuguese:   Piruvato Descarboxilase 
Synonyms English:   2 Oxo Acid Carboxy Lyase
2-Oxo Acid Carboxy-Lyase
Acid Carboxy-Lyase, 2-Oxo
Carboxy-Lyase, 2-Oxo Acid
Carboxylase, alpha-Ketoacid
Decarboxylase, Pyruvate
Decarboxylase, Pyruvic
Pyruvic Decarboxylase
alpha Carboxylase
alpha Ketoacid Carboxylase
alpha-Carboxylase
alpha-Ketoacid Carboxylase  
Tree Number:   D08.811.520.224.125.750
Definition English:   Catalyzes the decarboxylation of an alpha keto acid to an aldehyde and carbon dioxide. Thiamine pyrophosphate is an essential cofactor. In lower organisms, which ferment glucose to ethanol and carbon dioxide, the enzyme irreversibly decarboxylates pyruvate to acetaldehyde. EC 4.1.1.1. 
History Note English:   91(75); was see under CARBOXY-LYASES 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   22630 
Unique Identifier:   D011767 

Occurrence in VHL: 		 

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DeCS